# Shorten HIV Diagnostic Window with Cnpair’s Raw Materials

> Source: https://www.cnpairbio.com/shorten-hiv-diagnostic-window-with-cnpairs-raw-materials/
> Author: CNPAIR
> Published: 2026-07-30
> Updated: 2026-08-17

**[Fourth-generation HIV assays](https://pmc.ncbi.nlm.nih.gov/articles/PMC11600489/)**detect both HIV-1/2 antibodies and HIV-1 p24 antigen, enabling earlier diagnosis compared to antibody-only tests. Cnpair offers a comprehensive range of raw materials for HIV antibody and antigen detection, covering HIV-1 (Group M & O) antigen, HIV-2 antigen, and HIV-1 p24 antibodies, which fully meet the requirements of fourth-generation HIV immunoassays. Our raw materials facilitate earlier diagnosis and help minimize the risk of missed infections.

**Cnpair HIV Ag ＆ Ab Performance**

## 1 Outstanding Sensitivity & Specificity – Engineered for Accurate and Reliable IVD Reagents

Demonstrated excellent performance on CLIA, validated with 1,762 clinical samples, achieving 99.93% negative concordance (N=1,465) and 100% positive concordance (N=297).

 ![](https://www.cnpairbio.com/wp-content/uploads/2026/07/Performance-of-Cnpair-HIV-Antibody-Antigen-on-CLIA-Platform-300x237.png)

## 2 Ultra-Low Detection Limits – Unlocking Early Diagnosis with Unmatched Precision

Antibody Detection: LOD = 0.2 NCU/mL (HIV -1)

Antigen Detection: LOD = 2.5 U/mL

## 3 Excellent Stability – Consistent Performance from Production to Point-of-Care

Maintains consistent performance after 12 days at 37°C, with positive signal variation within ±30%, ensuring robust reagent stability.

 ![](https://www.cnpairbio.com/wp-content/uploads/2026/07/Thermal-Stability-of-Cnpair-HIV-Antibody-Antigen-at-37°C-300x217.png)

## 4 Verified with National Reference Panels – Rigorously Tested to Meet the Highest Regulatory Standards

Validated with the Chinese National Reference Panel for HIV Antibodies (HIV Ag/Ab Chemiluminescence Immunoassay), Cnpair's HIV antigen and antibody raw materials achieved 100% concordance, including HIV-1 Group O samples.

Antibody National Panel (48 samples in total)：

 ![](https://www.cnpairbio.com/wp-content/uploads/2026/07/National-Reference-Panel-Validation-Summary-300x141.png)

Antigen National Panel (This reference panel consists of a total of 40 samples)：

 ![](https://www.cnpairbio.com/wp-content/uploads/2026/07/HIV-Antigen-National-Panel-This-reference-panel-consists-of-a-total-of-40-samples-300x78.png)

Our raw materials facilitate earlier diagnosis and help reduce the risk of missed infections. Learn more about our [Sexually Transmitted Diseases solutions](https://www.cnpairbio.com/immunoassay-diagnostics/std/)