Native Antigen vs Recombinant Antigen: Which is right for your IVD Reagent Development?
Native antigens come from natural biological sources and retain conformational epitopes that recombinant antigens may not fully reproduce. Recombinant antigens offer scalable, consistent production but can differ in folding, glycosylation, and epitope presentation. For IVD development, native antigens are preferred when natural conformation and broad epitope coverage are critical.